mrd

Giulia Maddalena, a clinical oncologist by education and research trainee at MD Anderson Cancer Center, discusses how medical literature defines MRD and shares your survey results regarding what is your preferred definition. In cancer research, the importance of MRD has been growing, extending its relevance from hematologic malignancies to solid tumors. However, it stands for different definitions according to the specific context: Minimal Residual Disease, Molecular Residual Disease, or Measurable Residual Disease. This variability in terminology reflects the evolving nature of cancer diagnostics and treatment monitoring. Given the importance of clarity in medical terminology, we conducted a literature [...]

American Society of Clinical Oncology (ASCO) 2024 Annual Meeting is being held Friday, May 31st through Tuesday, June 4th, with numerous scheduled sessions related to minimal residual disease in colorectal cancer. Highlighted Sessions and Posters Use of MRD-Guided Strategies to Optimize Therapeutic Interventions Circulating Biomarkers: Who, What, Where, When, and Why? Gastrointestinal Cancer—Colorectal and Anal Abstracts and Posters Clinical validation of a novel circulating tumor DNA methylation assay for predicting recurrence of colorectal cancer in patients with curative-intent surgery by monitoring minimal residual disease. A phase II trial of TAS-102 in patients with colorectal cancer with ctDNA-defined [...]

Cancer Network posts 15-episode series "ASCO GI 2024: Updates in MRD Testing for the Management of Colorectal Cancer" in which medical oncologists highlight clinical trials presented at ASCO GI 2024 and discuss the utility of minimal residual disease (MRD) and circulating tumor DNA (ctDNA).

Cancer Network posts 10-episode series titled "Around the Practice: ctDNA in Treatment Decisions and Monitoring" in which expert oncologists discuss current and future use of minimal residual disease (MRD) and circulating tumor DNA (ctDNA) in colorectal cancer.